Agenda

Synthetic Biology for the Next Generation

A Symposium Under the Auspices of

The National Academy of Sciences and The National Academy of Engineering

June 12-13, 2012
The National Academy of Sciences Building
2101 Constitution Avenue, NW
Washington, DC 20418

At this National Academy of Sciences and National Academy of Engineering symposium, stakeholders examined the next-generation tools, platforms and infrastructure necessary for continued progress in synthetic biology - and the associated social and policy implications. The symposium was the final of a three-part series organized in conjunction with the Royal Society, the Royal Academy of Engineering, and the Chinese Academies of Science and Engineering. The symposium featured the following sessions:

• Meeting Global Challenges
• Overview of Research in Key Application Areas
• Organizational Strategies in Support of Synthetic Biology
• National Strategies for Advancing Synthetic Biology
• Perspectives on Synthetic Biology from within the Political System
• Rebuilding the Social Contract
• Exploring Fundamental Questions in Biology
• Advancing Fundamental Needs in Engineering
• Enabling the Next Generation of Leadership and Community
• Prudent Practice: Lessons from Real World Case Studies
• Ownership, Sharing, and Innovation
• Critical Issues for Success

Agenda

Tuesday, June 12, 2012

7:30 Continental Breakfast

8:00 Welcome

Charles Vest, President, The National Academy of Engineering

8:10 Meeting Global Challenges

Moderator: Pamela Silver, Harvard Medical School

Speakers:

Daniel P. Schrag, Harvard University
Saul Griffith, Engineer and Entrepreneur

9:00 Overview of Research in Key Application Areas

Moderator: Guo-ping Zhao, Shanghai Institutes for Biological Sciences

Speakers:

Jindong Zhao, Institute of Hydrobiology, Chinese Academy of Sciences
(Agriculture and Environment)
Gregory Stephanopoulos, Massachusetts Institute of Technology
(Industrial Applications)
Alexandra Daisy Ginsberg, Designer, Artist, and Writer
(Arts/Humanities)
Christina Smolke, Stanford University (Health and Medicine)

10:00 Discussion with Participants

10:15 Break

10:30 Organizational Strategies in Support of Synthetic Biology

Moderator: Rob Carlson, Biodesic

Speakers:

Lionel Clarke, Shell
Ian Fotheringham, Ingenza
Jason Kelly, Ginkgo BioWorks
Meagan Lizarazo, iGEM
Darlene Solomon, Agilent
Guo-ping Zhao, Shanghai Institutes for Biological Sciences

11:30 Discussion with Participants

11:45 Lunch

1:00 National Strategies for Advancing Synthetic Biology

Moderator: Jonathan Margolis, U.S. Department of State

Speakers:

Gerardo Jiménez-Sanchez, Organisation for Economic Cooperation
and Development
John Perkins, Department for Business, Innovation & Skills, U.K.
Government
Xian-en Zhang, Ministry of Science and Technology of China

2:00 Discussion with Participants

2:15 Perspectives on Synthetic Biology from within the Political System

Moderator: Aristides Patrinos, Synthetic Genomics

Speaker:

David Uffindell, Department for Business, Innovation & Skills, U.K.
Government
Jetta Wong, U.S. House of Representatives
Guo-ping Zhao, Shanghai Institutes for Biological Sciences

3:15 Discussion with Participants

3:30 Break

3:45 Roundtable Discussion – Rebuilding the Social Contract

Moderator: Jonathan Moreno, University of Pennsylvania

Speakers:

Jaydee Hanson, International Center for Technology Assessment
Thane Kreiner, Santa Clara University
Renzong Qiu, Chinese Academy of Social Sciences Institute of
Philosophy
Nikolas Rose, Kings College London
Edward You, Federal Bureau of Investigation
Laurie Zoloth, Northwestern University

4:45 Discussion with Participants

5:00 Adjourn

5:15 Reception in Great Hall

Wednesday, June 13, 2012

7:30 Continental Breakfast

8:00 Welcome

Drew Endy, Stanford University

8:10 Roundtable Discussion – Exploring Fundamental Questions in Biology

Moderator: Peter Leadlay, University of Cambridge

Keynote Address: Michael Elowitz, California Institute of Technology

Respondents / Discussants:

Maitreya Dunham, University of Washington
Paul Freemont, Imperial College London
Jason Micklefield, University of Manchester
Weiwen Zhang, Tianjin University

9:30 Discussion with Participants

9:45 Roundtable Discussion – Advancing Fundamental Needs in
Engineering

Moderator: Richard Kitney, Imperial College London

Discussants:

Peter Carr, Massachusetts Institute of Technology (Measures and
System Performance)
Todd Peterson, Life Technologies Corporation (DNA Synthesis,
Assembly, and Strain Engineering)
Cesar Rodriguez, Genome Compiler Corporation (Computer-Aided
Design/ Data Exchange)
Reshma Shetty, Ginkgo BioWorks (Metrology)
Zhihua Zhou, Shanghai Institutes for Biological Sciences (Genetically
Encoded Sensors)

10:45 Discussion with Participants

11:00 Break

11:15 Enabling the Next Generation of Leadership and Community

Moderator: Megan Palmer, Synthetic Biology Engineering Research Center
(SynBERC) and Stanford University

Discussants:

James Field, Imperial College London
Karmella Haynes, Arizona State University
Michael Jewett, Northwestern University
Chenli Liu, Guangzhou Institute of Advanced Technology

12:00 Discussion with Participants

12:15 Lunch

Roundtable Discussions – Governance: Needs Beyond the Bench

1:30 Session A: Prudent Practice - Lessons from Real World Case Studies

Moderator: David Rejeski, Woodrow Wilson International Center for Scholars

Discussants:

Patrick Boyle, Harvard University
Nikki Kapp, Imperial College London
Chris Schoene, Imperial College London
Gautam Mukunda, Harvard University
Zhongjun Qin, Shanghai Institutes for Biological Sciences

2:30 Discussion with Participants

2:45 Session B: Ownership, Sharing, and Innovation

Moderator: Drew Endy, Stanford University

Opening Remarks: Linda Kahl, Synthetic Biology Engineering Research Center
(SynBERC) and Stanford University

Discussants:

Arti Rai, Duke University
Daniel Kevles, Yale University
Nita Farahany, Vanderbilt University Law School
Mark Lemley, Stanford University

3:45 Discussion with Participants

4:00 Break

4:15 Roundtable Discussion – Critical Issues for Success

Moderator: Rick Johnson, Global Helix LLC

Discussants:

Francois Kepes, Le Centre national de la recherche scientifique
Carlos Olguin, Autodesk
Lynn Preston, National Science Foundation
Marc Salit, National Institute of Standards and Technology
Robert Wells, Organisation for Economic Co-operation and
Development
Youli Xiao, Shanghai Institutes for Biological Sciences

5:15 Discussion with Participants

5:30 Adjourn